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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf06b04da8f11dc66bb2c8b28c27bb3980bdadce510df7c0d3196cf01591b605' 
  AND token = 'HeQQG4pOEJVTTN2TYcYPETkZyS2P4x3SBc56nkyVrqs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}