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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e17827dcd5b67aec5e6c476da2a661d6d725d9186e1df9972aa87e0051c9a10' 
  AND token = '3D4akKm+78KG1ro0/PAPna4NBMkl5PCzigTR7ciyaJU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}