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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a67d42fcd3c1a5ffa24da7ea25580ac329862d65cbf01475528c7243bf5c1fc8' 
  AND token = 'DAd/RqtjszMbGO8XpzS3+Skmez7dVQm7lUrHMFVruJM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}