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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0267992d8b03c1f4fda17dd2be9bfacdc5a6980bdec2d2f37ac1c66697fa4308' 
  AND token = 'zCNCGxlFToGrs5XAGwT9F0RNhDn9IsMViNTdCuzoIfM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}