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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec20322fac6093faa7cda1133e7886269eadfd4c31f111283a7164d8c7c84771' 
  AND token = 'IsFvwxt1FGnOdRai27OEKp+WDBZZwR6aK9NO4vN/2oI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}