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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65db43cc1582f361206aa7acf7176003bd85a22050416972f86e11b631dfe3b4' 
  AND token = '3ZMlEkaz4hgiEKCqYuwM/NKPM1cEHKIFZTA3ql3qsQQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}