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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '47131389411d2df3aa0047405b92e4bcfb6f6f7adeedd857d0f057d28b7d6d74' 
  AND token = 'OA/I8OJyeowO49iIjwlMcfgUcqgfxTGxliNzrcjaEc4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}