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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64393f06d24916ad8ec0078e286cdb5ee9d49bfe71216febc08ac9d2f90a4e6b' 
  AND token = 'PTpziffnnzkWrqd7cs/Iaz33ZHhT6JV95EHX9qF8C8k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}