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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dc380d0e29c30942079d265999be2c3e1cff7eec8822a064e7951d476c7005c2' 
  AND token = 'Ky0fzfzW1wihLXj28/+Lu8/Ly8Zwl6HV28pSlS1FwrI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}