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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f08b73eacb9ce505a64eaf54c44859c59738c0e106e8ccac26c51b9fe2a5b54' 
  AND token = 'IRbXsG1/75lAn/X8wFX9oAFc6msqjcAiqjul0to+NvI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}