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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '223b63fa527ac91bf55744d696d31d6f12e6a55bd64a9bdb7fa2cc0d57bc15ab' 
  AND token = 'sWcb1mHKCId+GgWgJ/R12ZpuBB267OyKj2z3oXVKJAA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}