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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c58d5586e3371e8a0ad1cd7c3b6a4f00c9071335c78569eb3c100a369ac27041' 
  AND token = 'f/k8W41RTVUyBh2IFWFZaw6FhtNeWdenwMaU4yhAdFg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}