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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4aba0532acb1d22ce94bfa4d4feb8e80a014367139f2cf0be5b787d86949de57' 
  AND token = '4U20rPnWWjJJqEkCxuRCTKcsLAxRbg7wN30ecV5tyoo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}