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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd53773aff4b88b2e885c44f55e0715b016498418b985b12c42b91f19762cd004' 
  AND token = 'mfRLvTdXtgl6w5h7I7zxV9IbtXBYc0Bm+ZlYEH5L114=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}