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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '165af65c5a24ed13b3e185c36a27e833aa8c1707b3c3318580217942087c1424' 
  AND token = 'fLtQ4eAD5cyPvHPRnv+uvBcA63ulLvJQPQmQ6LCpZ28=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}