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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '491bee4a61667e0e62216a0f495f3e477ea3b792c1bd7d266690ceef397fd68d' 
  AND token = 'Zf40fXw7VE3wm5YJ3Y+6yU9TL1+79F+51JPPnY+NXTE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}