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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f4595c046b907b7ea1e178932710a70faed30437d257081d6d6174bfee65f9f' 
  AND token = 'pP7z/g/RHt1cmY8U3UVJ7croUTA3jIWnZn4lwFDC2SM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}