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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '308f6f562f4d567fa8e4640cb3e17a1122e292de3e44d41305d5bb3185e6217c' 
  AND token = 'SYaw4aKpBgBCi28L+l42ysu4tVreBqzDDE4ZceDj47E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}