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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bb2599ff548d1dab76e48449e315dc3c57dcb6761791502148642503c077441f' 
  AND token = 'gkxoz1z0AJxUF2AUs+t/NrAPE9yLpGNTqP0AfIU9DbI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}