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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6a047f3d8f2c368f3290fdc0b49e9cfde82a63736a41c31d5135df80b5d39de' 
  AND token = 'FTs8T6gMUcdHAF4I4eXpVyUpB1HAlcDjhL3cQsKxZNI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}