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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73269c176ad55f13c064562a234e5c4ef7547f82a9f636fe9e62158689c4138f' 
  AND token = 'uZ8r41fvWugckWm4dpXt2LNvUjmdGg4x3gHGvj7qOPI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}