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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8b01e2eda49103e8db93de8c93239428d1063e12d4a4e333778cd2104ce567b' 
  AND token = 'tFELONrfArhSFf6cAI4Fi3/18w4atOPHj9NbJzFr95I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}