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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8805c22caef40cc8fc9cdb893b34f6b84efb6cb9a64c89940533712c97a7e490' 
  AND token = '/ERcjrsRD8u/AeRs8N1E58sgPEo8ZVhEXugAgItrsuc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}