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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ae25f1358e01f29306cee9448dd8178392ace2cd1862227f256fa0e1b3f2b67' 
  AND token = 'iOmFmJTKWD57krUH1lToveriP8xrjoPcPr7VQ4Zf+X4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}