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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c0497d735480b34022548402511efa7e677c0b7af9a39b6530f8793bf4666af' 
  AND token = 'lRGweK8q3HX9p/rNZ0UHTBs9qTuxLUAKkKqiWEsqqQM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}