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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d6fa8fc67a53a2f645ef83bbdd50e3113f5163f8615317e2c1e71a6b44cb720' 
  AND token = 'Dxzx1BYZG7ZxbolGkgNKTvD87ABFggv1o/wuMeeRXjs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}