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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29026e449506b467b8612102efbe5f71d1ab5b5dfe9b424a48b6e824151aef0f' 
  AND token = 'CpGDh16VFq4eEs1zPxReNVoyVqiO8/byji58T5wFJJw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}