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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9f0a387ca47664cbc2c6e90b9d00ca41d8b41529357945fbfd3587558f7f890' 
  AND token = 'fwrgY3aY2x/dRdrW4vswFsR2V3pFrtdNUf4rd0HG1P8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}