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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c58cb0186fe306e4b840de4c5516fc5b49a659631c21fe3f8a479a65d6644b4' 
  AND token = 'lfCJfJLYUJFPo/L6IU8HqLe2pDGo2AvbNjwdWTi/aq0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}