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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e00f5c7e3f19f93975b5a7ec0105608aacf6e064443b3ae599fb1f76c9636baa' 
  AND token = 'WX1MNfDmY8l5oSfrnvkLOJ4RpHcFOHbNIfjTXXCGbEM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}