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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ea1e72c333ceced370a1184a7f6299a4fd3e98dd8f0f12315628799c8e83db0' 
  AND token = 'H5hYbM3wYQuk/frd+JDeV0llDl57N5c6aRaRhP9cM40=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}