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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80544e1ec3444c354bf8b534f13ec5b70e246e1c040087e7d64c41501ceb9d2c' 
  AND token = 'PouuVzUaOXXpPmTFYlHJmC5ppb/9477uzxmQVFOFcjo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}