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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f10728fd104e9659117ffe9398495a69664460fae7bc9689de81b5e6051fdbe' 
  AND token = '+HDfxdbTfALjmYoKP1C5v9XLKH+kz5YgLpiUpm3YSvM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}