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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '58cab6b98bbab00fcd03927b1307336ed9b8a72c86f6d984edab5216ae4ed7a1' 
  AND token = 'EEV29+IP2Dul2tzn1AeHYYZXBEklBaBs7f1zw7GNLRA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}