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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d7ad586f62cb95f982977b4e41620905ef64fe0545cbe7221e63e23d6f726da' 
  AND token = 'PQiuBH3pfuEoaPayciSLyRwyqNxPmCR8+nCoLlo3vrI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}