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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a79f0f3d6070d7a37534d3685c68ea4a34d45d0bb421542104bf77c020cda54' 
  AND token = '+V6dLRnvn2OJtgRRU9dkheNpSkUSl/10n72JoOBekTo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}