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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd7368f66da7a7279b491f3ff45e2622ca38c924ab3e422a7d086b4dad70f757f' 
  AND token = 'IZc0KNUzSRSy+21AhugI7p40qDA2YMIgHcRLsVTX7r0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}