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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b05d00b6482a4c0152006833d15201a514a9c2c4f3ffd77ab1c85ba33f182420' 
  AND token = 'NERsOs6Qz7bd/pV1HWDF3BP3zlf3UunGJsJ14JPIHAs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}