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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e18af901be25ee093a9bcdc2aca89d215d1b3f7d1032b03e3b5ccdff5dda782c' 
  AND token = 'pVOGvZBrO8UQbCYxCo8PY+61lK4Jf7zHc4Q8Hj7odQs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}