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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c2d96ac4f8bbd778ae4bdb73b3d054513d756d51c5142a89ea2e145561e49d7' 
  AND token = 'a+ubGtV9x/Z408CbnWOaJGpGepbgyfItPdG9cPxXm0w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}