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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5e63df8919b718e6a1cb9c8fa64ef5444834e3e7a3b6c305019fd415c20c2bb' 
  AND token = 'iJnPpkpdZQuVwsiG9uOeIWt719LvIGf7gRWx1zIDAY4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}