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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe296b35317c407627a479b7579175e5c1025bea61fd831fa24afbf41da24e66' 
  AND token = 'nxG05WbMWaBJXVb8mf6UtfCyl8QPH+TovcjH6NA2ZEs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}