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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c05f7f5640cd5ee0416bb7e2f21eae4060e019dfbdae29a4c8d5ec25ef278d3' 
  AND token = 'rJP8vOMeS+tgc/uoMilBRLLZOsbbHpCeLRpj3o1RP0g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}