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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88fc16bdbd84f6ea40b2ba57b4e412b85f68db44ff6c2f68fe7a78f955486e15' 
  AND token = 'yHMpRTm2xOeDmjP4j6KnPxit5GBKXIZmHKThg+GWn5c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}