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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d61ed8645ca308762e6afe9027999efa78f3d23040e15513eaad1840dbde261' 
  AND token = '5in3UXPEtwNAw4ZT5v9MPUKhJ8Cyhx4eX/+tAGV8roc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}