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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae7dfa1da0cc6ede9dd1d6779f9000b21b204fe25156bf29c0621f13198f96a0' 
  AND token = 'rKGLWs2rTlcKg5Rh0t59we5U0l47d1Ea/NxA1/R+kzM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}