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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80320a7c8bfb7336eecacee9f969d3f17440ebf35b99bda44d9172c1384ca1a6' 
  AND token = 'lI3mo3Lp39Ci/ODR9jUWr/xWPzIKLqJYmchoC5NdAC4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}