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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4589e05c9c775ae4a91ca4533150e06956bdb6dabeebce82cefb034f5b3229cf' 
  AND token = 'fIuEb12pYM/gH6g+uZSOC18cCDTFMOfMs1fb0RjKPhI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}