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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3ca839c7d0dc38bfe0196a862208ff78dd702ade1faa11f13b0279d766d0993' 
  AND token = 'z81vD7BC9Ezdb17eOHU5RggXvOk9PPobnKA8/ehkAek=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}