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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '822785c7d57f6000941e1d1a565fb6618bdcc7ee2cc042e7f4a407d6e35e05ad' 
  AND token = 'n5jYEo5JtZfBCDHpRnUmr3qnNp45wJzFvMlU8kYrmp8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}